Omega-3 Polyunsaturated Fatty Acids in Prevention of Mood and Anxiety Disorders.

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indexPsychiatric disorders in general, and major depression and anxiety disorders in particular, account for a large burden of disability, morbidity and premature mortality worldwide. Omega-3 polyunsaturated fatty acids (PUFAs) have a range of neurobiological activities in modulation of neurotransmitters, anti-inflammation, anti-oxidation and neuroplasticity, which could contribute to psychotropic effects. [1]

Here the authors reviewed recent research on the benefits of omega-3 PUFA supplements in prevention against major depression, bipolar disorders, interferon-α-induced depression patients with chronic hepatitis C viral infection, and posttraumatic stress disorder.

The biological mechanisms underlying omega-3 PUFAs’ psychotropic effects are proposed and reviewed. Nutrition is a modifiable environmental factor that might be important in prevention medicine, which have been applied for many years in the secondary prevention of heart disease with omega-3 PUFAs.

This review extends the notion that nutrition in psychiatry is a modifiable environmental factor and calls for more researches on prospective clinical studies to justify the preventive application of omega-3 PUFAs in daily practice.


[1] Su KP, Matsuoka Y, Pae CU. Omega-3 Polyunsaturated Fatty Acids in Prevention of Mood and Anxiety Disorders. Clin Psychopharmacol Neurosci. 2015 Aug 31;13(2):129-37 View Full Text


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  • There are 2 important biomarkers that you can use to assess if a person has the right amounts of Fatty Acids:

    Omega-3 Index……>8%…Is the Omega-3 level high enough
    Omega-6/3 Ratio…<3:1…Is the Omega-6 low enough to reduce Inflammation ?

    To learn more about these:
    USA – search for "Omegaquant"
    Outside USA – search for "GreenVits"



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