#Frankincense is a traditional medicine from the East believed to have many therapeutic properties, including creating an #anti-inflammatory effect. It is harvested from the resin of the #Boswellia tree and researchers believe that it can prevent the release of #leukotrienes, which are compounds that can cause #inflammation. One of its key, anti-inflammatory, substances is #boswellic acid, which makes it suitable for the treatment of diseases such as #asthma, #rheumatoid #arthritis and #neurodermatitis. A study by Friedrich Schiller University of Jena (Germany) and Louisiana State University, has now been published –Nature Chemical Biology– uncovering the molecular mechanism behind its anti-inflammatory effects.
- Published in News
Liquid gold. Golden milk. That brilliant saffron-hued spice. We hear a lot about turmeric these days—also known as Curcuma longa—a member of the ginger family, and native of Southeast Asia.[i] Valued for its brilliant hue and distinctive spicy-bitter flavor, its use as a dye, a spice, and in religious ceremonies dates back nearly 4000 years.[ii],[iii] Turmeric is a mainstay in Ayurvedic and Chinese medicine, thanks in large part to curcuminoids—three bright golden-colored, lipophilic polyphenols (curcumin, demethoxycurcumin and bisdemethoxycurcumin), collectively known as “curcumin” that are derived from the plant’s rhizomes.[iv],[v] The main component of the root is a volatile oil containing turmerone.
- Published in Reviews
Transcriptional Regulation of Inflammatory Pain and Hyperalgesia: NF-kB as a Lynchpin and Master Regulator.
The milieu and array of inflammatory cells and inflammatory mediators are crucially involved in the genesis, persistence and severity of pain following trauma, infection or nerve injury . The mechanisms and pathways mediating pain and nociception (hyperalgesia) are transcriptionally regulated. The transcriptional mediator nuclear factor (NF)-κB plays a major role in regulating inflammatory responses, ostensibly via the control of gene expression/suppression. An association has recently emerged to establish a possible link between NF-kB and pain/nociception, purportedly through the regulation of the inflammatory loop and the secretion (biosynthesis) of pro-inflammatory mediators.
- Published in Abstracts
Recent findings suggest that the amino acid glutamine reduces Helicobacter pylori-associated pathology in mice and may therefore have similar effects in humans with gastric ulcers caused by H. pylori.
- Published in Abstracts
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