FORGOT YOUR DETAILS?

Reading Time: 3 minutes

journalFor some years the notion that adverse responses to environmental triggers may be increasing due to a change in the ongoing exposure to mild immune activating bacteria has been gaining credibility. From Strachans first proposals to now there has been a continuous evolution of the hygiene hypothesis.[1],[2]

  • Hygiene hypothesis – criticised as being too vague, including by Professor Strachan himself
  • Microbial hypothesis (avoiding an overemphasis on cleanliness) and the
  • Old friends hypothesis (implying that microbes that were beneficial for immune system development have been eliminated or replaced).
  • Biodiversity hypothesis expands the hygiene hypothesis to the living environment in general,
  • Biome depletion model views the hygiene hypothesis as an evolutionary mismatch that works in tandem with other mismatches, such as inflammatory diets or vitamin A, D or K deficiency, which undermine immune function in westernised societies.
Tagged under: , , , , ,
TOP