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indexEosinophilic (ee-uh-sin-uh-fil-ik) oesophagitis (EoE) is a recognised chronic allergic/immune condition. A person with EoE will have inflammation of the esophagus. The oesophagus is the tube that sends food from the mouth to the stomach.

In EoE, large numbers of white blood cells called eosinophils are found in the tissue of the oesophagus. Normally there are no eosinophils in the oesophagus. The symptoms of EoE vary with age. In infants and toddlers, you may notice that they refuse their food or are not growing properly. School-age children often have recurring abdominal pain, trouble swallowing or vomiting. Teenagers and adults most often have difficulty swallowing, particularly dry or dense, solid foods. The oesophagus can narrow to the point that food gets stuck. This is called food impaction and it is a medical emergency.

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Eosinophilic Oesophagitis (EoE), first described in the early 1990’s, has rapidly evolved as distinctive chronic inflammatory oesophageal disease. The diagnosis is based clinically by the presence of symptoms related to an oesophageal dysfunction and histologically by an eosinophil-predominant inflammation once other conditions leading to oesophageal eosinophilia are excluded. This striking male-prevalent[1] disease has an increasing incidence and prevalence in the westernised countries. Currently, EoE represents the main cause of dysphagia and bolus impaction in adult patients.[2]

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