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Surprising new research demonstrates that diabetic neuropathy, an extremely painful condition, may respond to supplementation with the active forms of three b vitamins: methyl B12, methylfolate, and the active form of vitamin B6 (pyridoxal-5′-phosphate). In a 2011 study in the Review of Neurological Diseases, researchers reported that eleven diabetic patients with diabetic neuropathy were placed on these three supplements, and tested by means of punch biopsy before treatment and after six months of treatment. An astounding 73% of patients showed actual improvement in tissue on biopsy, and 82% reported reduced frequency and intensity of pain and numbness.(1)

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