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April of 2013 FOCUS introduced the latest research on mixed tocotrienols from organic virgin red palm oil, and in November 2013 we further explored these novel molecules. We feel the quote from Bharat B. Agarwahl, PhD, of the University of Texas M.D. Anderson Cancer Center in Houston, sums it up well: “Tocotrienols exhibit health benefits quite different from that of tocopherols, and in most cases, these activities are superior for human use. Promising oral agents like tocotrienols are bioavailable, work on multiple pathways, and are already recognised as safe.”

Prof. Dr Chandan a world expert on the role of tocotrienols and their role in health presented a short presentation in 2013 on the many benefits that can be attributed to the ingestion of Tocotrienols, we have discussed the interesting role of these vitamin E rich fats for the management of risk/prevention and recovery. In particular the reduction of stroke risk and the restoration of liver quality in people with fatty liver diseases or even greater risk of liver failure. Watch his presentation.

A recently published study that shows the synergistic effect of oral supplementation of d-mixed tocotrienols and alpha-tocopherol in improving non-alcoholic steatohepatitis rats. Non-alcoholic steatohepatits (NASH) is the most extreme form of non-alcoholic fatty liver disease (NAFLD), resulting from the accumulation of triglycerides/fats (fatty liver), oxidative stress and inflammatory in the liver.

Marilyn Arguillas is a gastroenterologist with a special interest in liver diseases particularly non-al­coholic fatty liver disease, chronic hepatitis, cirrho­sis and liver cancer. She is chair of Internal Med­icine-Gastroenterology at Davao Doctors Hospital in Davao City, Philippines. She was a member of the Executive Council of the Asian Pacific Associa­tion for the Study of the Liver (APASL) from 2006- 2010 and the President of the Hepatology Society of the Philippines from 2010-2012. In June of 2013 her findings on tocotrienols and fatty liver disease were presented as a Poster of Distinction by the Asian Pa­cific Association for the Study of the Liver (APASL) conference in Singapore.

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Vitamin E Treats Fatty Liver

The use of single nutrients for health management are often challenged due to lack of randomised controlled trials or small cohort size, or just general reluctance to regard these small molecules as anything other than a constituent of the mythical balanced diet.

There can be no denying that the increase in abdominal mass or obesity is not an imaginary event, even a cursory glance in your office or in the local town will identify significant differences in body mass. One of the consequences of this is the deposition of fats in the liver –an event referred to in simpler times as ‘fatty liver’ and now glorified with the name ‘non alcoholic steatohepatitis’ less comprehendible and definitely scarier.

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