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Saccharomyces is a non-colonising yeast used for the last 70 plus years as a therapeutic agent for the relief and management of gastrointestinal distress. Whilst its community use as a by-product of lychee fermentation was well understood in indo china and other nations, in particular for the relief of choleric dysentery it was after Henri Boulard set up the French pharmaceutical company to exploit its potential that studies began. So the recent publication (July 2014) of a review paper in the well known journal Pediatrics is a helpful means of qualifying its use in the paediatric population[1]

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