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The Guts Of The Matter

This seminar information explores the traditional model of calories in vs calories out as the explanation for weight gain, and identifies the flaws of this model. The seminar focuses on the biological addictive nature of the Western diet and sugar and how addiction determines food choice and caloric intake. It is possible that being fat makes you hungry, but there is also evidence that being hungry makes you fat. Learn about the role of the microbiome’s in metabolism. The influence of environmental toxins is explored and how this affects fat stores. Genetics play a role, but epigenetics is more significant in weight issues.

Apples; great for SCFA production, restoring bacterial eubiosis in a disrupted gut and likely able to assist with weight management, say scientists in the journal Food Chemistry.[1] Apples, in general, have shown to protect against human chronic diseases due to their content of fibre and phenolic compounds. These bioactive compounds have low availability and can potentially reach to colon, modulate the balance of bacterial populations in the gut, and influence the host physiology. The apple health benefits are, in part, due to the interaction of fibre and phenolics with gut microbiota that results in changes in phenolic bioavailability and activity, and the production of short chain fatty acids (SCFAs) after fibre fermentation.

Our gut as we all know is home to innumerable different bacteria — a complex ecosystem that has an active role in a variety of bodily functions. In a study published on the 13th May 2013 in Proceedings of the National Academy of Sciences,[1] a team of researchers finds that in mice, just one of key bacterial species plays a major part in controlling obesity and metabolic disorders such as type 2 diabetes.

The bacterium, unfamiliar to many of us and called Akkermansia muciniphila, digests the epithelial mucus and makes up 3–5% of the microbes in a healthy mammalian gut. But the intestines of obese humans and mice, and those with type 2 diabetes, have much lower levels. The researchers led by Patrice Cani, who studies the interaction between gut bacteria and metabolism at the Catholic University of Louvain in Belgium, decided to investigate the link.

It is fair to say that obesity is a substantial risk factor for serious illnesses, such as cardiovascular disease and diabetes. Patients are usually advised to reduce their weight by restricting caloric intake (dieting) and increasing the amount of daily exercise. Some experts also believe that lack of sufficient sleep may contribute to obesity. The questions asked by the researchers were: Can sleep and weight reduction be linked? Their results have been published in the Annals of Medicine.[1]

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There are numerous benefits related to maintaining a healthy body mass and apart from personal comfort and self esteem the reduction of excess fatty tissues has been proven to show a great deal of change in circulating markers of inflammation. Pro inflammatory cytokines are understood to be involved with a wide range of adverse health conditions and it is generally accepted that managing to keep these low molecular weight molecules in a state of balance will provide benefits to all tissues in the body – including the brain.

Two types of cytokine in particular are related to obesity – IL-6 and TNF-α and raised levels will undoubtedly have adverse effects and reduce capacity for a healthy life. This study out in GUT demonstrates that excessive weight loss is an effective anti-inflammatory strategy.[1]

Multi Vitamins are considered by many to be little more than colourful contributors to urine flow that reflect a gullible individuals need to add capital to the water course. I have addressed the major complications with this facile comment in a previous commentary.

A paper out in the March 2010 International Journal of Obesity[1] throws added weight to the triage theory of Prof Bruce Ames,[2] when additional nutrients were added to the dietary intake of obese Chinese females. It is already understood that obesity contributes to reduced bioavailability of minerals and vitamins and certainly contributes to reduced blood concentrations.

The team of researchers based at Harbin Medical University in China recruited 96 Chinese women with an average body mass index of 28kg/m2 and aged between 18-55 for the 6 month study.

Three groups were randomly set up, with one getting a multivimin, the next calcium only (162mg) and the last placebo. The results were compelling; the multivimin group had reduced body weight, body mass index, fat mass, total cholesterol and LDL cholesterol. On the positive side, they had an increased level of resting energy expenditure and HDL levels also increased. They also found reduced waist size and better breathing.

Date: February the 9th 2010 Times: Registration: 6.00pm   Presentation begins: 6.30pm  Concludes: 9.00pm Location: The Franklin Theatre The Institute of Physics, 76 Portland Place London W1B 1NT (map) Presenter: Antony Haynes BA(Hons) DipION mBANT Price: £31.65 ( also provides online access to presentation and handouts) What Is This About? In 2010, Nutri-Link’s Weight Loss

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