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S0091674909X00102_cov200hDr Harri Hemila MD. PhD responded to the CAM article in Allergy and Clinical Immunology [1] stating-

Mainardi et al[1] reviewed the use and effects of complementary and alternative medicines on respiratory symptoms. They stated that early studies on vitamin C did not demonstrate an effect on the duration or intensity of the common cold, and as a support to this statement, they referred to 2 articles from 1975.[2,3]

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generic.Par.0001.ImageDr Harri Hemila MD PhD co author of the Cochrane Review article replies [1]:

The Cochrane review was limited to placebo-controlled trials in which at least 0.2 g of vitamin C was used per day.[2] Most of these trials examined vitamin C administration as regular supplementation and provided strong evidence that vitamin C shortens the duration of colds and alleviates its symptoms.

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