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Bile Acids and Mucosal Immunity

Monday, 26 August 2019 by

The-Importance-of-Bile-Acids-to-our-HealthBile acids are critical for the digestion and absorption of fats and fat-soluble vitamins in the small intestine. Recent studies suggest bile acids have further functions as pleotropic signalling metabolites able to interact with germline-encoded host receptors and microbiota to regulate an array of #metabolic and #inflammatory pathways. Researchers from The Scripps Research Institute Florida and Osaka University Japan have recently published a piece discussing the interplay between bile acids, the microbiota and the mucosal immune system. They focus on how this interplay can regulate intestinal homeostasis and inflammation. The dynamic three-dimensional interplay between #bile acids, the microbiome and the mucosal immune system represents an important new frontier in the field of Mucosal Immunology. 

Stomach Acid and Allergies

Monday, 12 August 2019 by

Stomach-acid-and-allergies (002)Austrian scientists have established a link between stomach acid reducing prescription medicines and an increased risk of developing #allergies. Researchers had access to the health records of over 8 million Austrians over a four-year period and found that patients prescribed #gastric acid inhibitors were twice as likely to also be prescribed #anti-allergy drugs in the future.

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