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Thinning hair, painful joints,lost libido, vaginal dryness, hot flashes, night sweats, moodiness, crushing fatigue, difficulty concentrating, weight gain, itchy skin, incontinence…the list of symptoms during menopause is staggering. Staggering, but not surprising, since our cells are studded with receptors for hormones.

Vasomotor symptoms (hot flashes, night sweats), vaginal dryness, and dyspareunia (painful intercourse) are the main reason that women seek medical treatment. Over three-quarters of women report hot flashes within the 2 years surrounding menopause. A quarter suffer these symptoms for over five years, while an unfortunate ten percent of women report that they suffer from these symptoms for over ten years.1

00bookDiindolylmethane (DIM)
A phytonutrient and plant indole found in cruciferous vegetables including broccoli, brussels sprouts, cabbage, cauliflower and kale, with potential antiandrogenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial oestrogen metabolism in both sexes by reducing the levels of 16-hydroxy oestrogen metabolites and increasing the formation of 2-hydroxy oestrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown. Check for active clinical trials using this agent. (NCI Thesaurus)

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