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FAT? – I’m Not To Blame It’s My Genes!

Sunday, 04 April 2010 by | Comments: 4

Michael Ash BSc(Hons) DO ND FDipION reviews a selection of papers exploring the intersection between our genetic code and the style of food ingested in ever increasing amounts, in which fat and sugar make up the dominant components.

It’s clear from numerous studies that a sedentary lifestyle and a diet high in fat and sugar have profound effects on human mortality and morbidity through adverse weight gain.[1] The enormous human genome project, started in 2000 has also thrown up a number of markers in our approximately 21,000 genes related to an historical adaptive need to store fat when food was scarce and starvation an ever present threat. Some have interpreted this by saying that the reason they are obese or cannot lose weight is down to their genes, and that this may in turn abrogate them from actively altering lifestyle patterns, others have questioned the accuracy or validity of this causal relationship. [2],[3]

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