FORGOT YOUR DETAILS?

Thinning hair, painful joints,lost libido, vaginal dryness, hot flashes, night sweats, moodiness, crushing fatigue, difficulty concentrating, weight gain, itchy skin, incontinence…the list of symptoms during menopause is staggering. Staggering, but not surprising, since our cells are studded with receptors for hormones.

Vasomotor symptoms (hot flashes, night sweats), vaginal dryness, and dyspareunia (painful intercourse) are the main reason that women seek medical treatment. Over three-quarters of women report hot flashes within the 2 years surrounding menopause. A quarter suffer these symptoms for over five years, while an unfortunate ten percent of women report that they suffer from these symptoms for over ten years.1

Ghost Writing and the Human Cost of Hype

Wednesday, 29 September 2010 by

The commercial world of pharmaceuticals contains many bright and highly motivated scientists who genuinely want to develop or extend human knowledge to assist with the management or eradication of disease. As with all sectors of society there are those who are more diligent about their work than others, and there are those who seek to make a financial return regardless of the risks involved. A recent article in PLOS exposes the dramatic use of ghost writers and nefarious activities of Wyeth in their promotion of the menopausal hormone therapy Prempro (conjugated equine oestrogens [CEEs] and medroxyprogesterone acetate [MPA]).[1]

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525013Treatment based on resveratrol could be a safer alternative to hormone replacement therapy (HRT) in postmenopausal women and could help prevent breast cancer, according to a new study.

The findings of the study published in the Journal of Nutritional Biochemistry indicate that resveratrol is the most likely candidate of the phytoestrogens to offer safer HRT and chemoprevention of breast cancer due to its oestrogenic activity and high antitumour activity.

Phytoestrogens are natural plant substances found in food that exert weak oestrogen-like activity toward mammals, such as daidzein, genistein and glycitein found in soybeans and soy products, coumestrol in mung bean and alfalfa sprouts and resveratrol in grape skins and red wine.

Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from the National Centre for Health Statistics. Incidence and death rates are standardized by age to the 2000 United States standard million population.

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