FORGOT YOUR DETAILS?

Reading Time: 3 minutes

Over the more recent past a number of strands of evolving discovery indicate that subsets of commensal microbes materially influence the gut and associated mucosal immune system. In particular the peripherally generated regulatory T cell has been seen as a powerful addition in maintaining mucosal homeostasis in the gut and provides unique benefits not delivered by thymically induced Treg alone.

For instance, colonisation with the bacterium Clostridia promotes extrathymic generation of regulatory T (Treg) cells that have a central role in the suppression of inflammatory and allergic responses.

TOP