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In previous posts I have discussed the progressive emergence of a subset of patients with problems induced by foods driving immune changes in their oesophagus. Eosinophilic oesophagitis (EoE) is a chronic inflammatory disease with isolated eosinophils in the oesophagus predominantly triggered by foods.

Eosinophilic esophagitis (EoE) is characterised by an isolated infiltration of the oesophagus with eosinophil’s without infiltration in other parts of the gastrointestinal tract. The symptoms of EoE are similar to those of gastrointestinal reflux disease and include vomiting, abdominal pain, regurgitation, and dysphagia. The number of oesophageal eosinophils per high-power field (hpf) is required as part of the clinicopathologic diagnosis, which is defined as 15 or more eosinophils per hpf in a patient receiving a proton pump inhibitor.