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One of the questions that crops up in the clinical management of patients suspected of having coeliac disease, is: If my patient has been gluten free, or is going to try an exclusion from gluten containing foods, how long should they be free of gluten before undertaking a gluten challenge test?An article in GUT looks to explain this in some detail [1]

Our understanding of the pathophysiology of coeliac disease has advanced with associated improvement in diagnostic modalities. Recent studies have placed the prevalence of coeliac disease in Western populations at between 1:250 and 1:67. Coeliac disease is common throughout the world and most cases go undiagnosed. Understanding the risk factors, clinical presentations and diagnostic modalities is necessary to identify and treat patients with this commonly misdiagnosed disorder.

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