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2009coverPancreatic Proteolytic Enzyme Therapy Compared With Gemcitabine-Based Chemotherapy for the Treatment of Pancreatic Cancer.

Dr Gonzalez, a recent expert speaker at one of the NL expert education seminars, has had his therapy heavily criticised in this recent article published in the  respected Journal of Clinical Oncology.

At first sight it can seem that the paper roundly demolishes the pancreatic enzyme and lifestyle treatment recommended by Dr Gonzalez, and adds considerable value to the mixed chemotherapy treatment provided as the competing arm of the therapy.

In fact this paper has already been lauded in the arenas frequented by the more committed anti-alternative or non RCT evidenced medicine as a gross failure of the enzyme therapy to show any benefit in the care of pancreatic cancer patients.

Surely this must be considered an experts review, especially as the lead author Dr John Chabot was the appointed independent trial Principal Investigator at Columbia? He would know and report accurately what went on – wouldn’t he?

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00bookDiindolylmethane (DIM)
A phytonutrient and plant indole found in cruciferous vegetables including broccoli, brussels sprouts, cabbage, cauliflower and kale, with potential antiandrogenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial oestrogen metabolism in both sexes by reducing the levels of 16-hydroxy oestrogen metabolites and increasing the formation of 2-hydroxy oestrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown. Check for active clinical trials using this agent. (NCI Thesaurus)

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A 12-year study that followed over 60,000 Britons, half of whom were vegetarian, suggests that vegetarians had a lower risk of developing cancer than meat-eaters. The results showed that overall, vegetarians were 12 per cent less likely to develop cancer than meat eaters, while fish eaters were 18 per cent less likely (however fish eaters was also a smaller sample and potentially a less reliable statistic).

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suppl.1.coverVitamin C is commonly known to be essential to human health. However, specifically as it relates to cancer treatment, the value of vitamin C is debated and often considered a topic of scientific controversy. Cancer researchers have investigated various ways of administering high-dose vitamin C, including both orally and intravenously. Researchers have also examined different forms of vitamin C—ascorbic acid (AA) and dehydroascorbic acid (DHA)—which may well be a comparison of apples and oranges.

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Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from the National Centre for Health Statistics. Incidence and death rates are standardized by age to the 2000 United States standard million population.

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The most devastating loss of life from breast cancer impacts women between the ages of 30 and 50. For women between the ages of 40 and 44, breast cancer is the leading cause of death, according to the American Cancer Society. Yet the November 10, 2003 issue of the AMA journal, American Medical News, reports

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Background: Previous experimental studies have suggested many possible anti-cancer mechanisms for green tea, but epidemiologic evidence for the effect of green tea consumption on gastric cancer risk is conflicting.

Objective: To examine the association between green tea consumption and gastric cancer.

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Much debate has focused on whether antioxidants interfere with the efficacy of cancer chemotherapy. The objective of this study is to systematically review the randomized, controlled clinical trial evidence evaluating the effects of concurrent use of antioxidants with chemotherapy on toxic side effects.

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PURPOSE: Some in the oncology community contend that patients undergoing chemotherapy and/or radiation therapy should not use food supplement antioxidants and other nutrients. Oncologists at an influential oncology institution contended that antioxidants interfere with radiation and some chemotherapies because those modalities kill by generating free radicals that are neutralized by antioxidants, and that folic acid interferes with methotrexate. This is despite the common use of amifostine and dexrazoxane, 2 prescription antioxidants, during chemotherapy and/or radiation therapy.

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Comment: An herb recently found to kill pancreatic cancer cells also appears to inhibit development of pancreatic cancer as a result of its anti-inflammatory properties, according to researchers from the Kimmel Cancer Center at Jefferson. The data were presented at the AACR 100th Annual Meeting 2009 in Denver.

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