Fibromyalgia is a condition of complex aetiology and up to 2% of the population with a higher frequency in females are currently diagnosed.
The symptom profile includes chronic, widespread pain, abnormal processing of pain and increased sensitivity to external stimuli, along with fatigue, gastrointestinal symptoms and changes in memory, mood and sleep.
The use of natural agents to enhance function and reduce symptoms have had variable and inconsistent results, albeit that a common pathway associated with mitochondrial dysfunction has been elucidated.
A paper out in 2018[1] in the International Journal of Clinical Medicine found evidence in a small cohort of participants for the safe and effective use of membrane replacement therapy (an organic source of membrane specific lipids)and low dose caffeine in the successful reduction in symptoms and improvement in quality of life.
Reference
[1] Nicolson, G.L., Settineri, R., Ferreira, G. and Breeding, P. Reduction of pain, fatigue, gastrointestinal and other symptoms and improvement in quality of life indicators in fibromyalgia patients with Membrane Lipid Replacement glycerolphospholipids and controlled-release caffeine. Intern. J. Clin. Med. 2018; 9: 560-579. View Full Paper
