Noncommunicable diseases (#NCDs), also known as chronic diseases, happen as a result of a combination of genetic, physiological, environmental and behavioural factors, and are not transmissible directly from one person to another. The main types of NCDs are #cardiovascular diseases, #cancer, #asthma and #diabetes, and they now account for 70% of all deaths globally. The definition of NCDs rules out any microbial involvement, but data is increasingly showing us that the microbiota of individuals with various NCDS has been altered. Scientists have transplanted dysbiotic microbiota from animal models of NCDs into healthy animals which have resulted in the disease. The Canadian microbiologist Brett Finlay has recently written an article in Science Mag proposing that some NCDs could have a microbial component capable of communicability via the microbiota.

The foods we eat commonly affect our #gut #microbiota by triggering the production of #bacteriophage, which are the viruses that infect and replicate inside #bacteria. The #microbiome is made up of hundreds of different bacteria and the #phages they host. Researchers from San Diego State University have discovered a new way to harness food as medicine by identifying common dietary compounds that can kill specific bacteria without affecting others.

More people are living longer thanks to the rise in life expectancy, unfortunately this also means that more people are living with diseases such as #diabetes, #cancer and #heart disease. Modifiable lifestyle factors including #smoking, #exercise, #alcohol consumption, #obesity and #diet quality can all affect both total life expectancy and the incidence of chronic disease. Many studies have shown that smoking, inactivity, heavy alcohol consumption and a poor-quality diet contribute towards a high percentage of premature deaths as well as a loss of years in life expectancy. A new study published in the peer-reviewed British Medical Journal, includes data from more than 110,000 people and focuses on the effect of healthy lifestyle factors on a life expectancy free of cancer, cardiovascular disease and type 2 diabetes.

Whilst our ancestors’ diets would obviously have excluded highly refined foods, new research has been released to show that what they did include was starchy #carbohydrates, something that may cause disbelief amongst many ardent #paleo diet followers. During an excavation at the Border Cave in the Lebombo Mountains, scientists from the Wits Evolutionary Studies Institute at the University of the Witwatersrand in Johannesburg, have discovered well preserved pieces of fibre rich, carb-heavy, #rhizomes, dated up to 170,000 years ago. This find is at least 50,000 years earlier than previous examples of cooked carbohydrates being eaten.

‘You are what you eat’, the maxim made memorable thanks to Jean Anthelme Brillat-Savarin in 1826, is as important now as it was then. The vital role #diet plays in #health has been widely documented, but our understanding widely rests on the 150 #nutritional components tracked by national databases which only represent a small section of the 26,000 definable biochemicals in the food supply. This wide range of chemical diversity remains largely invisible both to us and to epidemiological studies, yet the number is only expected to rise as detection techniques improve, leading to a far greater understanding of the links between our diet and health.

Published in the European Heart Journal, a pioneering new study from the Tulane University Obesity Research Center, has found that those people with a high genetic risk of #heart disease or #stroke could offset that risk with a healthy #sleep pattern. Scientists conducted a large-scale study with 385,292 participants from the UK Biobank, using them to create a genetic risk score to determine whether individuals were at high, intermediate or low risk of #cardiovascular problems. The participants were followed for 8 years, during this time they recorded 7,280 cases of heart attack or stroke. The lead researcher, Dr. Lu Qi, developed a series of health questions in order to develop a “sleep score” for the participants, considering #insomnia and #snoring, as well as hours spent asleep.

The negative effects of polluted air on our physical health is well documented and emerging evidence is now highlighting the damage it can also cause to our #mental health. University College London have conducted the first systematic review and meta-analysis of evidence connecting air #pollution to a range of mental health problems. The team of researchers reviewed data from 16 countries, looking in detail at 25 studies published up to late 2017, the results have been published in Environmental Health Perspectives.

#BPA (#bisphenol A) is a chemical added to many commercial products, that when mixed with other compounds, produces strong and resilient plastics. BPA-containing plastics are commonly found in food containers, drinks bottles, hygiene products and are used to make epoxy resins that line canned foods. The health effects on the body of BPA products has proved a controversial subject. A new analysis, in the peer-reviewed Lancet Diabetes and Endocrinology Journal, suggests that BPA chemical levels in humans has been drastically underestimated based on a new method for evaluating exposure.

A new study published in Cell Metabolism, by the Salk Institute for Biological Studies, California, offers evidence that limiting your daily eating window to 10 hours can be beneficial to our health, promoting #weight loss, improving #sleep and preventing #diabetes.  #Intermittent #fasting has been rapidly growing in popularity and encompasses everything from skipping one meal a day to fasting a few days a week, in contrast to this, #time-restricted eating  simply requires a person to consume all of their daily calories within a ten hour window.

#Mitochondria are the parts of cells that turn #sugars, #fats and #proteins into forms of chemical energy that the body can use to carry on living. They are #organelles that are found in the cells of every complex #organism and produce around 90% of the chemical energy required for cells to survive. They are the only organelles to retain their own genome and the communication abilities of transcription and translating in order to harvest energy. Their complex communication network allows them to stay in tune with #cellular needs and nuclear transcriptional programs and to alleviate mitochondrial dysfunction. Swiss cytologists have published a review of recent findings on the wide array of different mechanisms that contribute to these mitocellular communication networks.