FORGOT YOUR DETAILS?

Home Of Immune Memory Found

Wednesday, 03 June 2009 by

New findings overturn a major model of where immune memory is stored. Rather than circulating throughout the body, as researchers had thought, memory T-cells actually reside in a comfortable niche in the bone marrow waiting for the next chance to fight infection, according to a new article published online in Immunity today (May 7th). Immunologists have long believed that memory cells come from activated effector T cells that have resigned their ability to fight, and simply remain in circulation until they are re-activated a second time by the same pathogen they initially attacked. Researchers have now found that rather than remaining in the circulation as previously thought, the majority return to the bone marrow, 80% of them are found here. These cells remained there for up to 134 days — the length of time the researchers tested.

Tagged under: , ,

The relationship between autism and vaccination remains a heated one. Quite polarised views about the rights and wrongs of vaccination are to be found amongst parents and scientists. Naturally disproving a theory can sometimes be harder than proving it and doubt remains in the minds of many advocates of the vaccination and autism model. The following paper provides an overview of the current arguments and whilst it will be uncomfortable reading for the dedicated proponents it raises some good questions.

Tagged under: ,

Background: Telomere length may be a marker of biological aging. Multivitamin supplements represent a major source of micronutrients, which may affect telomere length by modulating oxidative stress and chronic inflammation.

BACKGROUND: Human herpesvirus-6 (HHV-6), Epstein-Barr virus and parvovirus B19 have been suggested as aetiological agents of chronic fatigue syndrome but none of these viruses is consistently detected in all patients. However, active viral infections may be localised in specific tissues, and, therefore, are not easily detectable. The aim of this study was to investigate the presence of HHV-6, HHV-7, EBV and parvovirus B19 in the gastro-intestinal tract of CFS patients.

The efficacy of a 2-month treatment with oral colostrum in the prevention of flu episodes compared with anti influenza vaccination was evaluated. Groups included healthy subjects without prophylaxis and those receiving both vaccination and colostrum. After 3 months of follow-up, the number of days with flu was 3 times higher in the non-colostrum subjects.

Gluten-Free Diet Bad for Gut Health

Thursday, 21 May 2009 by | Comments: 2

Comment: Spanish researchers recently found a gluten-free diet (GFD) led to reductions in beneficial gut bacteria populations and the ability of faecal samples to stimulate the host’s immunity (Br J Nutr. 2009). The effects of a GFD on the composition and immune function of the gut microbiota were analysed in 10 healthy subjects (mean age 30.3 years) over a period of one month.

Comment: Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which affects approximately six percent of the world population and is also a primary cause of stomach cancer. But today the bacteria is growing increasingly resistant to antibiotics.

Tagged under: , ,

There has been significant public debate about the susceptibility of research to biases of various kinds. The dialogue has extended to the peer-reviewed literature, scientific conferences, the mass media, government advisory bodies, and beyond. Whereas biases can come from myriad sources, the overwhelming focus of the discussion to date has been on industry-funded science.

Tagged under: ,

A large body of literature suggests that higher intakes of omega-6 (or n-6) polyunsaturated fatty acids (PUFAs) reduce risk for coronary heart disease (CHD). However, for the reasons outlined below, some individuals and groups have recommended substantial reductions in omega-6 PUFA intake. The purpose of this advisory is to review evidence on the relationship between omega-6 PUFAs and the risk of CHD and cardiovascular disease.

Maternal infection during pregnancy increases the risk of schizophrenia and other brain disorders of neurodevelopmental origin in the offspring. A multitude of infectious agents seem to be involved in this association. Therefore, it has been proposed that factors common to the immune response to a wide variety of bacterial and viral pathogens may be the critical link between prenatal infection and postnatal brain and behavioural pathology.

TOP