Inorganic lead is undoubtedly one of the oldest occupational toxins and evidence of lead poisoning can be found dating back to Roman times. It is a contaminating metal that has received much attention as the causative agent of one of the significant silent types of poisoning in the modern world. Industrial lead production started at

Mammals, that probably represent the most sophisticated metazoans, show an highly complex pattern of interactions between the immune and the neuroendocrine systems (Weigent and Blalock, 1987, 1995). However, in an evolutionary perspective, the roots of these interactions must be traced back to the defense mechanisms which are also present in simpler (and older) forms of

Tagged under: , ,

As more and more people are writing about medicine, alternative medicine and other subjects in which a reference is required it is sometimes useful to have consistent approaches to building that all important reference list. There is an increasing willingness to use blogs as sources, or other web pages. This web page called Citing Medicine

Tagged under: , , , ,

The most devastating loss of life from breast cancer impacts women between the ages of 30 and 50. For women between the ages of 40 and 44, breast cancer is the leading cause of death, according to the American Cancer Society. Yet the November 10, 2003 issue of the AMA journal, American Medical News, reports

Folate (the naturally occurring form) and folic acid are forms of a water-soluble B vitamin (B9) that were first synthesized in 1945. Folate functions as an important cofactor in the transfer and use of 1-carbon moieties, primarily methyl groups. An important advance in understanding subclinical folate deficiency came in 1991 with the demonstration that folic acid supplementation before and during pregnancy dramatically reduced the risk of neural-tube defects in newborns. Folate supplementation of women before and during the first trimester of pregnancy has a dose-response effect in preventing neural-tube defects, ranging from a 23% reduction with 200 μg to an 85% reduction with 5000 μg of folic acid per day. The strong evidence demonstrating reduced risks of neural-tube defects led to mandatory folic acid fortification of cereal grain products in the United States by January 1, 1998. Fortification of foods with folic acid in the United States costs about $1,000 per neural-tube defect prevented. Even with all the information on the benefits of folate, many studies show inadequate folate intake among young women. Adequate folate levels have also been associated with reduced risks of coronary artery disease, colorectal cancer, and dementia.

Psychiatry’s leadership is scrambling and fumbling in its effort to explain why it’s collusion with industry for pay is okay. Ever wondered how toxic psychoactive drugs that have been shown to be clinically insignificant have been catapulted into multi-billion dollar blockbuster sellers despite the fact that these drugs pose serious safety risks? Read more

“Vitamin D deficiency is common worldwide and could be a novel risk factor for the development of coronary artery atherosclerosis,” says Ramachandra B. Naik, MD, of the Barbara Davis Centre for Childhood Diabetes, University of Colorado, Denver. Dr. Naik presented study results indicating that although vitamin D (25-OHD) deficiency is not increased among type 1 diabetes patients, a deficiency in this patient population is associated with the initiation and acceleration of coronary artery calcification.

A recently published evidence-based review of irritable bowel syndrome (IBS) management and the release of online patient tools by the American College of Gastroenterology (ACG) may help diagnose the disease with fewer costly tests and guide IBS therapy decisions. The online interactive patient tools consist of both a questionnaire to help patients determine whether their

Tagged under: ,

Emergency department visits for nonspecific abdominal pain, especially among young women, may be tied to the prevailing level of air pollution. Data from Environment Canada’s National Air Pollution Surveillance were used to determine the hourly levels of ozone, nitrogen dioxide, sulphur dioxide, carbon monoxide and particulate matter of varying sizes. The data were matched with daily ED visit patterns for nonspecific abdominal pain. The investigators determined that nearly two-thirds of visits for this complaint were by women, and the majority of those women were between the ages of 15 and 24. Young women are the most affected cohort because they are at increased risk for functional motility disorders, the most common of which is irritable bowel syndrome.”

Recent findings suggest that the amino acid glutamine reduces Helicobacter pylori-associated pathology in mice and may therefore have similar effects in humans with gastric ulcers caused by H. pylori.