FORGOT YOUR DETAILS?

‘Nutritional Dark Matter’

Monday, 20 January 2020 by

Nutritional dark matter‘You are what you eat’, the maxim made memorable thanks to Jean Anthelme Brillat-Savarin in 1826, is as important now as it was then. The vital role #diet plays in #health has been widely documented, but our understanding widely rests on the 150 #nutritional components tracked by national databases which only represent a small section of the 26,000 definable biochemicals in the food supply. This wide range of chemical diversity remains largely invisible both to us and to epidemiological studies, yet the number is only expected to rise as detection techniques improve, leading to a far greater understanding of the links between our diet and health.

heart health benefits of a good good sleepPublished in the European Heart Journal, a pioneering new study from the Tulane University Obesity Research Center, has found that those people with a high genetic risk of #heart disease or #stroke could offset that risk with a healthy #sleep pattern. Scientists conducted a large-scale study with 385,292 participants from the UK Biobank, using them to create a genetic risk score to determine whether individuals were at high, intermediate or low risk of #cardiovascular problems. The participants were followed for 8 years, during this time they recorded 7,280 cases of heart attack or stroke. The lead researcher, Dr. Lu Qi, developed a series of health questions in order to develop a “sleep score” for the participants, considering #insomnia and #snoring, as well as hours spent asleep.

Air pollution linked to depession and suicideThe negative effects of polluted air on our physical health is well documented, emerging evidence is now highlighting the damage it can also cause to our #mental health. University College London have conducted the first systematic review and meta-analysis of evidence connecting air #pollution to a range of mental health problems. The team of researchers reviewed data from 16 countries, looking in detail at 25 studies published up to late 2017, the results have been published in Environmental Health Perspectives.

Underestimated Risks of BPA

Friday, 10 January 2020 by

Underestimasted risks of bpa#BPA (#bisphenol A) is a chemical added to many commercial products, that when mixed with other compounds, produces strong and resilient plastics. BPA-containing plastics are commonly found in food containers, drinks bottles, hygiene products and are used to make epoxy resins that line canned foods. The health effects on the body of BPA products has proved a controversial subject. A new analysis, in the peer-reviewed Lancet Diabetes and Endocrinology Journal, suggests that BPA chemical levels in humans has been drastically underestimated based on a new method for evaluating exposure.

Tagged under: ,

eating all meals within 10 hours aids healthA new study published in Cell Metabolism, by the Salk Institute for Biological Studies, California, offers evidence that limiting your daily eating window to 10 hours can be beneficial to our health, promoting #weight loss, improving #sleep and preventing #diabetes.  #Intermittent #fasting has been rapidly growing in popularity and encompasses everything from skipping one meal a day to fasting a few days a week, in contrast to this, #time-restricted eating  simply requires a person to consume all of their daily calories within a ten hour window.

Mitocellular Communication

Thursday, 19 December 2019 by

Mitocellular communication#Mitochondria are the parts of cells that turn #sugars, #fats and #proteins into forms of chemical energy that the body can use to carry on living. They are #organelles that are found in the cells of every complex #organism and produce around 90% of the chemical energy required for cells to survive. They are the only organelles to retain their own genome and the communication abilities of transcription and translating in order to harvest energy. Their complex communication network allows them to stay in tune with #cellular needs and nuclear transcriptional programs and to alleviate mitochondrial dysfunction. Swiss cytologists have published a review of recent findings on the wide array of different mechanisms that contribute to these mitocellular communication networks.

Lavender and Anxiety

Thursday, 12 December 2019 by

Lavender and anxietyWith #anxiety one of the most prevalent mental health conditions in the UK and more than 45 million working days a year being lost due to it, finding effective, safe treatments is a priority for practitioners.  Whilst psychological therapies can be incredibly effective for patients living with anxiety, they can be very hard to gain access to. The predominant treatments prescribed in general practice are selective serotonin reuptake inhibitors (#SSRIs), Serotonin and noradrenaline reuptake inhibitors (#SNRIs), #pregabalin and #benzodiazepines. Whilst beneficial in alleviating symptoms in many, these drugs come with side effects. #Lavender has traditionally been used for its calming benefits, recent research led by Davide Donelli from Careggi University Hospital, Florence, aimed to assess its efficacy, in any form of administration, on anxiety and anxiety related conditions. 

Tagged under: , ,
nm.3625-F1

Unraveling the Truth About Antioxidants: ROS and disease: finding the right balance. https://www.ncbi.nlm.nih.gov/pubmed/24999942

Antioxidant Therapies Address Common Underpinnings of These Chronic Conditions

There is not a day that goes by that healthcare practitioners don’t face challenges. Attending to many complex patients stacked back-to-back, communicating bad news to a patient, working with insurance to cover labs—most physicians encounter at least one of these, if not all three, each and every day. One of the additional challenges we face with complex patients is addressing a long list of diagnoses; as integrative providers, we often find ourselves trying to treat not just one, but often three or four health concerns in a single visit. With our broad education and tolle totum (treat the whole person) vision, it is difficult to avoid this tendency.

Fortunately, there are many nutritional therapies that address conditions we commonly see coexisting. Here, we look at factors in a set of conditions that commonly overlap: chronic fatigue syndrome, depression, and insomnia. More importantly, we discuss some shared solutions that will help the integrative practitioner support patients with these difficulties.

Common Underpinnings

Research Suggests Bile Acids Have Potential as a Therapy for Dysbiosis, Constipation, and Inflammatory Bowel Disease

Generally, when we think of bile, we first think of the role it plays in digestion. Produced by the liver and expelled into the digestive tract by the gallbladder, bile is the substance that serves to emulsify and break down dietary fats so that they can be absorbed in the small intestine. Thus, supplemental bile acids with meals may be important for individuals post-cholecystectomy or with fat malabsorption for other reasons. However, the effects and potential therapeutic benefits of bile acids in the body go far beyond this.

In the digestive tract, bile acids also affect the balance of flora and gut motility.[1],[2] Outside of the gut, they regulate many critical facets of physiology, including glucose and cholesterol metabolism; activating farnesoid X receptor (FXR), pregnane X receptor, the vitamin D receptor, and various G-protein-coupled receptors.[5] Evidence also suggests that bile acids affect neurological function, as well as the response of the hypothalamic–pituitary–adrenal axis.[6] Bile acids have even been suggested to be “novel therapeutic modalities in inflammation, obesity, and diabetes.”[7]

Passé? Or Something to Consider?

Nowadays, with any mention of digestive symptoms of constipation, diarrhoea, gas, or bloating, and a history of antibiotic or proton-pump inhibitor use, one of the first things most integrative healthcare practitioners will consider in the differential diagnosis list is gastrointestinal dysbiosis with testing for small intestinal bacterial overgrowth (SIBO).[1] SIBO has a lot of hype—and how can it not, with so many conferences, practitioners, and clinics focused on its treatment? Given that the lactulose breath test (LBT), commonly used for the diagnosis of SIBO, has a low sensitivity and frequently gives false-positive results (although sensitivity can be improved via three-hour methane and hydrogen testing), it can be overused for the ease of diagnosing, well, something.[2],[3]

TOP