A new study finds that when young people binge drink alcohol, it disrupts their immune system — and that disruption happens more quickly than drinkers might think.

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(2014) Antony Haynes: Auto Immunity 3

Tuesday, 16 September 2014 by

Auto-immunity has risen to the number one leading cause of mortality and morbidity in the world. You will be given an overview of the disposing factors required for the development of auto-immune conditions, including infections but focusing on dysbiosis & the relevance of the gastrointestinal microbiome. Case histories of patients with auto-immune conditions with dysbiosis are presented and how and what nutritional intervention supported a positive outcome.

Can proline-rich polypeptides (PRPs) protect your brain and even boost brain function? Studies in vitro on animals and humans support that idea. The neuro-protective cytokines in PRPs have a remarkably stabilizing effect on cognitive function in Alzheimer’s disease patients. In vitro studies show that PRPs inhibit fibrils and amyloid plaques.[1] PRPs also modulate intracellular levels of reactive oxygen species (ROS), by regulating glutathione metabolism and antioxidant enzymes.[2] Gene expression analysis found that PRPs down-regulate genes involved in inflammatory pathways and increase levels of an Amyloid-beta (Aβ) hydrolyzing enzyme.[3] When given orally to mice, PRPs improve motor and sensory activities.[4] When mice are given either PRPs or plain colostrum, the PRP supplemented mice swim faster to a hidden platform.[5] PRPs also improve spatial learning and memory in older rats.[6]

“Diet is a central issue when it comes to preserving our gastrointestinal health, because by eating and digesting we literally feed our gut microbiota, and thus influence its diversity and composition,” says the distinguished microbiota expert Professor Francisco Guarner (University Hospital Valld’Hebron, Barcelona, Spain).

If this balance is disturbed, it might result in a number of disorders, including functional bowel disorders, inflammatory bowel diseases and other immune mediated diseases, such as coeliac disease and certain allergies. Also, metabolic conditions, such as type 2 diabetes, and perhaps even behavioural disorders, such as autism and depression, can be linked to gut microbial imbalances. Although a disrupted microbial equilibrium can have many causes — infectious pathogens or use of antibiotics among them — the role of our daily food and lifestyle is crucial. Thus, the maintenance of our gastrointestinal health is to a considerable extent in our own hands.

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Garlic has long been recognised as a malodorous but important medical plant with a wide range of health supporting properties. Until recently when Turmeric overtook it, it had the greatest number of research papers in PubMed for a food derived health supporting ingredient. In relation to its content of small molecule chemistry, garlic not only has antibacterial properties; it has antiviral, antifungal and antiprotozoal properties as well, and it has beneficial effects on the cardiovascular and immune systems.[1]

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(2013) Antony Haynes: Auto Immunity 2

Thursday, 21 November 2013 by


Antony Haynes provides a functional medicine perspective on a variety of auto-immune conditions. He presents the information in a series of case histories from his clinical practice. The focus of this presentation is on the metabolic processes involved in the body’s and liver’s  biotransformation (detoxification) pathways which require support when addressing the total viral load or the toxic load within a patient with an auto-immune condition.

Vitamins Prime Immunity

Wednesday, 05 December 2012 by

Whilst the recognition has existed for many years that deficiency in nutrients and vitamins compromises immune function, some gaps have existed in our understanding.

Whilst I have covered the role of the lipid soluble vitamins A and D in various articles in terms of their immune modulating effects, a research paper out in the Nov 2012 Journal, Nature helps to expand some of the relationships between certain B vitamins and immune functionality.[1]

Faecal Transplant (FT) and IBD

Tuesday, 25 September 2012 by | Comments: 2

I have explored the role of appropriate transplantation in the resolution of MRSA infection that fails to resolve with antibiotic therapy, and have intimated that other conditions of the bowel and linked tissues may also benefit. The model is: that loss of mucosal tolerance underlies the pathology of inflammatory bowel disease and is also linked to irritable bowel syndrome. These altered states of function reflect a combination of environmental, genetic and emotional events that coalesce into a wide range of conditions.

A provocative article published in Nature Immunology[1] identifies the abject failure of public health’s policy of targeting diet and lifestyle changes in the reversal of the obesity epidemic. They also identify that obesity is a pro inflammatory state and as such promotes many of the chronic non infectious diseases and weakens immune resistance to infections that contribute to early death.

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Breast is Best for Gut Bacteria

Wednesday, 09 May 2012 by

Whilst the findings may seem consistent with our current understanding of the relationships between the gastrointestinal tracts bacterial maturation and immune functionality – the relationship between competence and breast milk, from a neonate’s immune perspective has been expanded following the publication of this study in Genome Biology.[1]