Coeliac Disease is Four Times More Common Now than in the 1950’s
Coeliac disease is an autoimmune disorder triggered by gluten, a protein in wheat, barley, rye and spelt. Currently, the only treatment available is the adoption of a lifelong gluten free diet, which is made particularly challenging due to the ubiquity of wheat in western diets. It is an excellent example of environmental challenge meeting gene susceptibility, and is a unique example of how exclusion of an environmental trigger can resolve the symptoms.
“Celiac disease has become much more common in the last 50 years, and we don’t know why,” said Dr Joseph Murray, the Mayo Clinic gastroenterologist who led the study. “…Obviously human genes haven’t changed, but something has changed in our environment to make this disease more common.”
Rubio-Tapia A, Kyle RA, Kaplan EL, Johnson DR, Page W, Erdtmann F, Brantner TL, Increased prevalence and mortality in undiagnosed celiac disease. Kim WR, Phelps TK, Lahr BD, Zinsmeister AR, Melton LJ 3rd, Murray JA.Gastroenterology. 2009 Jul;137(1):88-93. Epub 2009 Apr 10. View Abstract
One Response to “Coeliac Disease is Four Times More Common Now than in the 1950’s”
Leave a Reply
8th October 2016
The role of the complex community of microbial dwellers inside our digestive tract remains a valuable, but still poorly understood resource in which changes to density and variety can have significant effects on human function and health. One of the roles of these organisms is in the generation of endogenous defence molecules including the master antioxidant, glutathione.Click for further information
30th March - 3rd April 2017
Applying Functional Medicine in Clinical Practice is a well-orchestrated, comprehensive, patient centered educational programme that helps you deepen your clinical understanding and practical application of the Functional Medicine Matrix ModelClick for further information
- Once you have your food selection sorted, exerc...
Dietary Fibre and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular PathwaysIn June 2016 Cell Reports a well-respected scie...
- The American Addictions Centre have created a w...
- Antony Haynes BA(Hons) RNT undertakes a review ...
- Humic Acid This is a review of the anti-viral p...
Updates on your email
Don't miss out on our email updates