Butyric acid: what is the future for this old substance?
A recent paper in the journal Swiss Medical Weekly explored the developing uses for the application of butyric acid in the management of human health.
Butyric acid (BA) is a carboxylic acid with the formula CH3-CH2-CH2-COOH. It is frequently used in the veterinary field, especially in ruminant animals. Together with other short-chain fatty acids (propionic acid and acetic acid), BA is the principal source of energy produced by ruminal fermentation of cellulose and starch. In the field of zootechnics, butyric acid is used to improve the growth of bovine animals. In humans, BA is synthesised by the colonic microflora (microbiota) during fermentation of digestible fibre, such as cereal flour, inulin, and psyllium.
In humans, the effects of BA can be subdivided into intestinal and extraintestinal. Intestinal effects include: regulating transepithelial transport, improving the inflammatory and oxidative states of the intestinal mucosa, reinforcing the mucosal barrier, modulating visceral sensitivity and motility, and preventing and inhibiting colon carcinoma. Extraintestinal effects are less well known; they have been studied in vitro and in animal models and sometimes even in humans. Currently investigated effects include: haemoglobinopathies, hypercholesterolaemia, reducing resistance to insulin (in animal studies), and reducing ischemic stroke (in animal studies).
Additional information can be found by reading the short article in full.
 Sossai P. Butyric acid: what is the future for this old substance? Swiss Med Wkly. 2012 Jun 6;142:w13596. doi: 10.4414/smw.2012.13596. Review.
 Gorka P, Kowalski ZM, Pietrzak P, Kotunia A, Jagusiak W, Holst JJ, et al. Effect of method of delivery of sodium butyrate on rumen development in newborn calves. J Diary Sci. 2011;94:5578–88. View Abstract
- Is docosahexaenoic acid, an n–3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioural tests in humans and animals
- Folic Acid Mediates Post Partum Depression – Eventually
- Folic Acid-Indication: Parkinson’s Disease (PD)
- Has Mandatory Folic Acid Supplementation Of Foods Increased The Risk Of Asthma And Allergic Disease?
- Gluten Sensitivity: Real or Not
30th March - 3rd April 2017
Applying Functional Medicine in Clinical Practice is a well-orchestrated, comprehensive, patient centered educational programme that helps you deepen your clinical understanding and practical application of the Functional Medicine Matrix ModelClick for further information
- Antony Haynes BA, RNT explores some of the mate...
Dietary Metabolites and The Gut Microbiota: An Alternative Approach to Control Inflammatory and Autoimmune DiseasesMay 2016 saw the publication of an open access ...
- Antony Haynes, BA, RNT explores two key questio...
- The Journal of Nutrition published a review pap...
- Dr Carrie Decker ND explores the relative risk ...
Updates on your email
Don't miss out on our email updates