Butyric acid: what is the future for this old substance?
A recent paper in the journal Swiss Medical Weekly explored the developing uses for the application of butyric acid in the management of human health.
Butyric acid (BA) is a carboxylic acid with the formula CH3-CH2-CH2-COOH. It is frequently used in the veterinary field, especially in ruminant animals. Together with other short-chain fatty acids (propionic acid and acetic acid), BA is the principal source of energy produced by ruminal fermentation of cellulose and starch. In the field of zootechnics, butyric acid is used to improve the growth of bovine animals. In humans, BA is synthesised by the colonic microflora (microbiota) during fermentation of digestible fibre, such as cereal flour, inulin, and psyllium.
In humans, the effects of BA can be subdivided into intestinal and extraintestinal. Intestinal effects include: regulating transepithelial transport, improving the inflammatory and oxidative states of the intestinal mucosa, reinforcing the mucosal barrier, modulating visceral sensitivity and motility, and preventing and inhibiting colon carcinoma. Extraintestinal effects are less well known; they have been studied in vitro and in animal models and sometimes even in humans. Currently investigated effects include: haemoglobinopathies, hypercholesterolaemia, reducing resistance to insulin (in animal studies), and reducing ischemic stroke (in animal studies).
Additional information can be found by reading the short article in full.
 Sossai P. Butyric acid: what is the future for this old substance? Swiss Med Wkly. 2012 Jun 6;142:w13596. doi: 10.4414/smw.2012.13596. Review.
 Gorka P, Kowalski ZM, Pietrzak P, Kotunia A, Jagusiak W, Holst JJ, et al. Effect of method of delivery of sodium butyrate on rumen development in newborn calves. J Diary Sci. 2011;94:5578–88. View Abstract
4th - 8th Ocotber 2018
Applying Functional Medicine in Clinical Practice is a well-orchestrated, comprehensive, patient centered educational programme that helps you deepen your clinical understanding and practical application of the Functional Medicine Matrix ModelClick for further information
- Dr Carrie Decker ND, explores the terminology a...
- Female Hormones are still very much at the hear...
Grape Seed Extract and The Gut Microbiota – A New Understanding of The Interplays and Their Impact on HealthGrape seed extract by no means is “new” to the ...
- Dr Carrie Decker ND explores some of the mechan...
- Outdoor air pollution is contributing to about ...
Updates on your email
Don't miss out on our email updates