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Historic Artefacts As complex organisms surviving in a world of molecular and physical challenges our long ancestry has meant we have evolved a remarkably complex system of defence and repair. Regular insults have played a major role in natural selection traits and diverse defence mechanisms have evolved to support our survival and reproduction in the

ajg_cimageA paper in the American Journal of Gastroenterology looks at various markers to see if it is possible to use them to differentiate between IBS and IBD.[1]

Objectives:

Irritable bowel syndrome (IBS) is viewed as a diagnosis of exclusion by most providers. The aim of our study was to perform a systematic review and meta-analysis to evaluate the utility of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), faecal calprotectin, and faecal lactoferrin to distinguish between patients with IBS and inflammatory bowel disease (IBD) and healthy controls (HCs).

cover_natureA study in Nature suggests that common food additives could be contributing to the development of chronic inflammatory diseases. Chassaing et al.[1] report that dietary emulsifiers induce low-grade inflammation in mice by disrupting the composition of their intestinal microbiota, thereby predisposing these animals to the development of metabolic syndrome and colitis. This builds on an earlier paper they published in the Journal of Toxicologic Pathology.[2]

To explore the effects of emulsifying agents on the intestinal mucosa, the authors administered carboxymethylcellulose (CMC) or polysorbate 80 (P80), which are emulsifiers commonly used in human foods, to mice in their drinking water. Compared with control mice, animals that received the emulsifiers showed reduced mucus thickness and increased gut permeability.

indexOral immunoglobulin (Ig) preparations are prime examples of medicinal nutrition from natural sources. They are frequently used by Nutritional Therapists to confer a health benefit to patients with gastrointestinal disorders. A review paper, and open access as well looked at the capabilities and possible health benefits of using these in clinical care.[1]

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Probiotics may improve a person’s health by regulating their immune function. Some trials have shown that probiotic strains can prevent respiratory infections. Even though the previous version of our review showed benefits of probiotics for acute upper respiratory tract infections (URTIs), several new studies have been published.

NEUThe relationships between magnesium deficiency and human health are extensive. Whilst this is an animal model the possibility that some of the benefits seen from magnesium supplementation may be mediated through its effects on the gut microbiota is an interesting twist.

The paper published in Acta Neuropsychiatry in Feb 2015 sheds some light on the possible mechanisms involved.[1]

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currentCoverSummary review by Antony Haynes BA, RNT, promoted by attendance to a lecture presented by Professor Dale Bredesen MD, Augustus Rose Professor, Director, Easton Center for Alzheimer’s Disease Research, UCLA Founding President, Buck Institute

QRBResearchers and contemporary nutrition scientists, media and individuals have long debated how and what our ancestors ate. One of the early proposals by Charles Darwin hypothesised that the hunting of game animals was a defining feature of early hominids, linked with both upright walking and advanced tool use and that isolated these species from their closest relatives (such as ancestors of chimpanzees); contemporised versions of this hypothesis exist to this day. Other insist that while our ancestors’ diets did include meat, it was predominantly scavenged and not hunted. Still others argue that particular plant foods such as roots and tubers were of greater importance than meat in the diets of these species. You know the routine, depending on the veracity of the proponent, one or other tends to become contextualised and propagated as the correct, or at least the closest to correct as someone can be in the 21st century.

s13379569Dec 2013 saw a paper published in Interdisciplinary Toxicology that explored the notion that the popular herbicide called Roundup may have a relational link to its increased use.[1] In addition a number of other complex and distressing health conditions have been are increasingly attributed to this chemical.

Glyphosate was not originally designed as a herbicide. Patented by the Stauffer Chemical Company in 1964, it was introduced as a chelating agent. It avidly binds to metals. Glyphosate was first used as a descaling agent to clean out mineral deposits from the pipes in boilers and other hot water systems.

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IBD and C Difficile Infection

Thursday, 12 February 2015 by

XLargeThumb.00054725-201502000-00000.CVMany patients with diarrhoea diagnosed with inflammatory bowel disease (IBD) are not routinely checked for Clostridium difficile infection (CDI), researchers have found.[1]

This organism is well understood to have a correlative risk for increasing symptoms and reducing therapeutic intervention effectiveness and 5% of IBD patients are found with CDI.

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